pharma lecture woooooo (not)

objectives

focus is on steroidal and non steroidal anti inflammatory drugs

when we talk about anti inflammatory drugs, first to come in mind is this pathway that uhhhhhh results in the production of inflammatory mediators either via these genase things

corticosteroids inhibit this step of the inflammatory mechanism + other antiinflammatory mechanism mentioned later

non steroidal → inhibit cyclooxygenase enzyme (COX1, 2) → inhibit of prostaglanding release

• prostaglandins → arise from thromxoane? → latent a????
  • prostaglanding e2? fever,
  • you will need to know about prostaglanding

action of prostaglandin is specific to the tissue they’re produced in, mediatecd by …… (slide)

TXA AND PGI have opposing effect?